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Synthesis of 3-amino-1-methyl-5H-pyrido[4,3-b]indole-1-14C (TRP-P-2)

✍ Scribed by E. J. Reist; W. W. Bradford; G. R. Gordon; J. H. Peters


Publisher
John Wiley and Sons
Year
1984
Tongue
French
Weight
191 KB
Volume
21
Category
Article
ISSN
0022-2135

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✦ Synopsis


Abstract

A practical 2‐step synthesis of 3‐amino‐1‐methyl‐5H‐pyrido[4,3‐b]indole‐1‐^14^C is described, starting from 2‐cyanomethyl indole and carbonyl‐labeled acetyl chloride.


📜 SIMILAR VOLUMES


Synthesis of 5-fluoro-3-[3-[4-(2-[14C]-5
✍ Ute J. Haynes; J. E. Swigor 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 French ⚖ 209 KB

## Abstract The synthesis of 5‐Fluoro‐3‐[3‐[4‐(2‐[^14^C]‐5‐methoxy‐4‐pyrimi‐dinyl)‐1‐piperazinyl]propyl]‐1H‐indole dihydrochloride (5) was achieved by coupling [^14^C] formamidine acetate (1) and dimethylmethoxymalonate in methanol containing sodium methoxide at 60°C to provide 2‐[^14^C] 4,6‐dihydr