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ChemInform Abstract: Methyl 3-Amino-1H-indole-2-carboxylates in the Synthesis of 5H-Pyrimido[5,4-b]indole Derivatives.

โœ Scribed by A. S. Shestakova; Kh. S. Shikhaliev; O. E. Sidorenko; V. G. Kartsev; S. V. Simakov

Publisher
John Wiley and Sons
Year
2010
Weight
59 KB
Volume
41
Category
Article
ISSN
0931-7597

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โœ J. BERGMAN; H. VALLBERG ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 29 KB

Synthesis of 5H-Pyrazino(2,3-b)indoles from Indole-2,3-dione Derivatives. -The reaction of the N-acetylisatins (I) with ethylenediamine yields the products (III). After dehydrogenation these compounds and their analogues (IV) after deacetylation are cyclized by heating to the title products (VI). N