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Synthesis of 3-(2-pyridyl)-2-substituted-quinazolin-4(3H)-ones as new analgesic and anti-inflammatory agents

✍ Scribed by V. Alagarsamy; V. Raja Solomon; M. Murugan; R. Sankaranarayanan; P. Periyasamy; R. Deepa; T. Durai Anandkumar

Book ID: 116313790
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 435 KB
Volume: 62
Category: Article
ISSN: 0753-3322
DOI: 10.1016/j.biopha.2006.10.003

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A variety of 3-(4-methyl phenyl)-2-substituted amino-3H-quinazolin-4-ones were synthesized by reacting the amino group of 2-hydrazino-3-(4-methyl phenyl)-3H-quinazolin-4-one with a variety of aldehydes and ketones. The starting material 2-hydrazino-3-(4-methyl phenyl)-3H-quinazolin-4one was synthesi