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Synthesis of 3-(2-Aminoethyl)pyrrole Derivatives

✍ Scribed by Vassilis J. Demopoulos


Book ID
112128898
Publisher
Journal of Heterocyclic Chemistry
Year
1988
Tongue
English
Weight
320 KB
Volume
25
Category
Article
ISSN
0022-152X

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Substituted pyrrole derivatives are prepared by treatment of 2,3-dihydrofuran derivatives with trifluoroacetic acid. These in turn are obtained by Michael addition of carbon nucleophiles of the b-dicarbonyl type to N-(4-toluenesulfonyl)-N-(tertbutyloxycarbonyl)-dehydroalanine methyl ester.