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Synthesis of 3-(1H-tetrazol-5-YL)chromones and a novel degradation reaction of tetrazole ring with vilsmeier reagents

✍ Scribed by Akira Nohara


Publisher
Elsevier Science
Year
1974
Tongue
French
Weight
160 KB
Volume
15
Category
Article
ISSN
0040-4039

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Synthesis of [14C]KT3-671, 2-Propyl-8-ox
✍ Naoto Ueyama; Takashi Yanagisawa; Tsuyoshi Tomiyama πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 French βš– 263 KB πŸ‘ 1 views

## Abstract 2‐Propyl‐8‐oxo‐1‐[(2′‐(1H‐tetrazole‐5‐yl) biphenyl‐4‐yl)methyl]‐4, 5, 6, 7‐tetrahydrocyclohept imidazole (KT3‐671), which has been found to be a potent and selective angiotesin II receptor antagonist, was synthesized in ^14^C‐labelled form by using potassium[^14^C]‐cyanide. [^14^C](KT3‐