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Synthesis of [2H3]-dextromethorphan and its major urinary metabolites [2H3]-dextrorphan and [2H3]-dextrorphan-β-glucuronide

✍ Scribed by Georg Heinkele; Gerhard Schänzle; Thomas E. Mürdter

Publisher
John Wiley and Sons
Year
2002
Tongue
French
Weight
77 KB
Volume
45
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

Starting from dextromethorphan, [^2^H~3~]‐dextrorphan‐β‐glucuronide was synthesized in four steps with [^2^H~3~]‐dextromethorphan and [^2^H~3~]‐dextrorphan as intermediates with an overall yield of 11%. Copyright © 2002 John Wiley & Sons, Ltd.

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