𝔖 Bobbio Scriptorium
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Synthesis of 2‐Deoxy‐2‐Fluoro‐2‐ C ‐Methyl‐ D ‐Ribofuranoses

✍ Scribed by Clark, Jeremy L.; Christian Mason, J.; Hobbs, Ann J.; Hollecker, Laurent; Schinazi, Raymond F.


Book ID
123619482
Publisher
Taylor and Francis Group
Year
2006
Tongue
English
Weight
138 KB
Volume
25
Category
Article
ISSN
0732-8303

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## Abstract A convenient method for the synthesis of ^18^F‐2‐deoxy‐2‐fluoro‐D‐glucose (4) and ^18^F‐2‐deoxy‐2‐fluoro‐D‐mannose (8) by the direct fluorination of 3,4,6‐tri‐0‐acetyl‐D‐glucal with ^18^F‐F~2~ is described. ^14^C‐2‐deoxy‐2‐fluoro‐D‐glucose has been synthesized from ^14^C‐3,4,6‐tri‐0‐ace