Synthesis of 2,6-naphthyridine and some of its derivatives

✍ Scribed by Rosita Tan; Alfred Taurins

• Publisher: Elsevier Science
• Year: 1965
• Tongue: French
• Weight: 259 KB
• Volume: 6
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)99534-6

✦ Synopsis

A paper by G. Giacomello et al (1) prompts us to report on a recent work carried out in this laboratory dealing with a synthesis of 2,6-naphthyridine by the following routes. Ethyl 3-pyridylacetate (I) was treated with 30% H202 in glacial acetic acid for 24 hours at 65-70' to obtain ethyl 3-pyridylacetate N-oxide (II), white crystals, m-p. 97-98O. Found: C, 59.721 N, 4.961