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Synthesis of 2,5-disubstituted 1,3,4-oxadiazoles from trichloromethylarenes and acylhydrazines

✍ Scribed by I. S. Poddubnyi; L. I. Belen'skii; M. M. Krayushkin

Publisher
Springer US
Year
1994
Tongue
English
Weight
630 KB
Volume
30
Category
Article
ISSN
0009-3122

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A new synthesis of symmetrical 2,5-disub
A new synthesis of symmetrical 2,5-disubstituted 1,3,4-oxadiazoles
✍ Fouad Bentiss; Michel LagrenΓ©e πŸ“‚ Article πŸ“… 1999 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 182 KB πŸ‘ 1 views

## Abstract Several new 2,5‐disubstituted 1,3,4‐oxadiazoles have been synthesized in good yields by reaction of aromatic acids with hydrazine dihydrochloride in a mixture of orthophosphoric acid, phosphorus pentoxide and, in general, with addition of phosphorus oxychloride to the reaction mixture.