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Synthesis of 2(3H)-benzoxazolone and 2(3H)-benzothiazolone derivatives as potential beta-3-adrenergic receptor ligands (part 2)

✍ Scribed by J. F. Delhomel; S. Yous; P. Depreux; D. Lesieur


Publisher
Journal of Heterocyclic Chemistry
Year
2001
Tongue
English
Weight
91 KB
Volume
38
Category
Article
ISSN
0022-152X

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✦ Synopsis


Abstract

Adrenoceptors beta‐3‐subtype mediate lipolysis and in the search for potential beta‐3‐adrenergic receptors agonists for the treatment of obesity, we designed new arylethanolamines (structures 4, 5) and aryloxypropanolamines (structures 6, 7) derived from 2(3__H__)‐benzoxazolone and 2(3__H__)‐benzothiazolone.


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ChemInform Abstract: Synthesis of 2(3H)-
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