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Synthesis of 2(3H)-benzoxazolinone derivatives as potential beta-3-adrenergic receptor ligands

✍ Scribed by J. F. Delhomel; S. Yous; P. Depreux; D. Lesieur

Publisher
Journal of Heterocyclic Chemistry
Year
1999
Tongue
English
Weight
336 KB
Volume
36
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

Beta‐3‐subtype‐adrenoceptors mediate lipolysis and in the search for potential beta‐3‐adrenergic receptor agonists for the treatment of obesity, we designed new arylethanolamines, structures B~1~ and B~2~, derived from 2(3__H__)‐benzoxazolinone. To obtain these target compounds as starting materials, various N‐benzyl‐[2(3__H__)‐benzoxazolinon‐6‐yl]ethylamines were used.

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