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Synthesis of 2,3-disubstituted pyridines. o-Formylation and o-acylation of 2-alkylpyridines

โœ Scribed by Sanders, Edward B.; Secor, Henry V.; Seeman, Jeffrey I.

Book ID
126193315
Publisher
American Chemical Society
Year
1976
Tongue
English
Weight
301 KB
Volume
41
Category
Article
ISSN
0022-3263

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A facile synthesis of 2,3-disubstituted
A facile synthesis of 2,3-disubstituted furo[2,3-b]pyridines
โœ Gregory L. Beutner; Jeffrey T. Kuethe; Nobuyoshi Yasuda ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 174 KB

In a three-step sequence starting from readily available starting materials, 2,3-carbon disubstituted furo[2,3-b]pyridines can be accessed in good yields and purity. Furo[2,3-b]pyridines bearing ester, amide and ketone groups at the 2-position can be prepared with a variety of aryl and alkyl groups