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Synthesis of 2′,3′-Dideoxyinosine

✍ Scribed by Webb, Robert R.; Wos, John A.; Martin, John C.; Brodfuehrer, Paul R.

Book ID
120323352
Publisher
Taylor and Francis Group
Year
1988
Tongue
English
Weight
281 KB
Volume
7
Category
Article
ISSN
0732-8311

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## Abstract 2′,3′‐Dideoxyinosine‐^13^C~5~ (ddI‐^13^C~5~) and the related 2′,3′‐dideoxyadenosine‐^13^C~5~ (ddA‐^13^C~5~) were prepared from (S)‐5‐[^13^C~5~]2,3‐dideoxyribonolactone 1. From a batch of this starting material ddI‐^13^C~5~ was made in 27% overall yield in seven steps and ddA‐^13^C~5~ in