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Synthesis of 2-substituted benzimidazoles and bis-benzimidazoles by microwave in the presence of alumina-methanesulfonic acid

โœ Scribed by K. Niknam; A. Fatehi-Raviz


Book ID
113009735
Publisher
Iranian Chemical Society
Year
2007
Tongue
English
Weight
166 KB
Volume
4
Category
Article
ISSN
1735-207X

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The synthesis of benzoxazoles and benzimidazoles is accomplished by treating N,Odiacylated 2-aminophenols or NWdiacylated 1,2-phenylenediamines with p-toluenesulfonic acid under reflux in xylenes or toluene. These reactions are operationally simple and proceed in excellent yield.