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Synthesis of 2-substituted 7-methylpyrimido[4,5-d]pyrimidin-4(3H)-ones catalyzed by heteropolyacids

✍ Scribed by Fang, Zheng Dong; Fang, Di; Tan, Yu Yuan


Book ID
120766118
Publisher
Springer Netherlands
Year
2013
Tongue
English
Weight
297 KB
Volume
41
Category
Article
ISSN
0922-6168

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## Abstract Isoxazolo[5,4‐__d__]pyrimidine‐4,6(5__H__,7__H__)diones **2a**–**2f** have been synthesized from the reaction of ethyl 5‐amino‐3‐methyl‐4‐isoxazole carboxylate (**1**) with aryl isocyanates in the presence of Keggin heteropolyacid H~3~[PW~12~O~40~] as a green solid acid catalyst at roo