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Synthesis of 2-Oxo-2H-[1,2,4]oxadiazolo-[2,3-c]pyrimidine-5-carbamates

โœ Scribed by Urs Hengartner; Jean-Claude Muller; Henri Ramuz


Publisher
John Wiley and Sons
Year
1983
Tongue
German
Weight
242 KB
Volume
66
Category
Article
ISSN
0018-019X

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โœฆ Synopsis


Abstract

Thermal cyclization of the pyrimidineโ€Nโ€oxide dicarbamate 2 gives a 95:5 mixture of the 2โ€oxoโ€2__H__โ€[1,2,4]oxadiazolo[2,3โ€a]โ€ and [2,3โ€c]pyrimidinecarbamates 3 and 4. An efficient procedure for the conversion of 3 to 4, and vice versa, is described.


๐Ÿ“œ SIMILAR VOLUMES


Regioselective Synthesis of 2-oxo-2,8-di
โœ Jean-Claude Muller; Henri Ramuz ๐Ÿ“‚ Article ๐Ÿ“… 1982 ๐Ÿ› John Wiley and Sons ๐ŸŒ German โš– 467 KB

The synthesis of new 2โ€oxoโ€2,8โ€dihydroโ€[l,2,4]โ€oxadiazooโ€[2,3โ€__a__] pyrimidineโ€carbamates **3** described in this paper is based upon a regioselective heterocyclization of the pyrimidineโ€2,6โ€bis (alkoxycarbonylamino) __N__โ€oxides **4.** Structural and mechanistic aspects of that cyclizalion are dis