The synthesis of new 2โoxoโ2,8โdihydroโ[l,2,4]โoxadiazooโ[2,3โ__a__] pyrimidineโcarbamates **3** described in this paper is based upon a regioselective heterocyclization of the pyrimidineโ2,6โbis (alkoxycarbonylamino) __N__โoxides **4.** Structural and mechanistic aspects of that cyclizalion are dis
โฆ LIBER โฆ
Synthesis of 2-Oxo-2H-[1,2,4]oxadiazolo-[2,3-c]pyrimidine-5-carbamates
โ Scribed by Urs Hengartner; Jean-Claude Muller; Henri Ramuz
- Publisher
- John Wiley and Sons
- Year
- 1983
- Tongue
- German
- Weight
- 242 KB
- Volume
- 66
- Category
- Article
- ISSN
- 0018-019X
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โฆ Synopsis
Abstract
Thermal cyclization of the pyrimidineโNโoxide dicarbamate 2 gives a 95:5 mixture of the 2โoxoโ2__H__โ[1,2,4]oxadiazolo[2,3โa]โ and [2,3โc]pyrimidinecarbamates 3 and 4. An efficient procedure for the conversion of 3 to 4, and vice versa, is described.
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## Abstract For Abstract see ChemInform Abstract in Full Text.