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Synthesis of 2-Oxazolines Mediated by N,N′-Diisopropylcarbodiimide.

✍ Scribed by Stefano Crosignani; Abigail C. Young; Bruno Linclau


Publisher
John Wiley and Sons
Year
2005
Weight
22 KB
Volume
36
Category
Article
ISSN
0931-7597

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Synthesis of 2-oxazolines via boron este
✍ Baris Ilkgul; Deniz Gunes; Okan Sirkecioglu; Niyazi Bicak 📂 Article 📅 2010 🏛 Elsevier Science 🌐 French ⚖ 271 KB

A new, convenient, one-pot process is presented for the synthesis of 2-oxazolines in high yields (75-94%) via boron esters of N-(2-hydroxyethyl) amides. The procedure involves thermolysis of the boron esters at 240-260 °C, in the presence of solid CaO as an acid scavenger and allows the preparation