Mild, room temperature CrCl 2 reduction of 1,1,1-trichloroalkanes stereoselectively generates (Z)-1-chloro-2-substituted-1-alkenes in excellent yields.
Synthesis of 2-functionalized 1-chloro-1-iodo-1-alkenes from 1-chloro-1-alkynes and IPy2BF4
✍ Scribed by José Barluenga; Miguel A. Rodríguez; Pedro J. Campos
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- French
- Weight
- 196 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
A reagent system CF3CC13/Zn(>2 mol)/Ac20 transformed aldehydes to 2-chlorol.l,l-trifluoro-2-alkenes exclusively, whereas CF3CC13/ZnO2 mol)/AlCl3(cat.) converted aldehydes into 2-chloro-l,l-difluoro-1-alken-3-01s.
Reductive coupling of I -chloro-2-iodoperfluorocyclobutene (I), cyclopentene (Ill) and cyclohexene (VI) has been carried out with copper powder and a trace amount of dimethylformamide to give the corresponding 2,2'-dichloroperfluoro-(bi-1-cycloalken-1-yl) derivatives in 69x, 36% and 73% yield, respe
CrCl 2 converts trichloromethylcarbinols under mild conditions to (E)-a-haloalkylidene chromium carbenoids which add to aldehydes or are quenched with water affording 2-haloalk-2(Z)-en-1-ols and 1-chloro-1(Z)-alkenes, respectively, in high yield.