𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of 2′-Deoxyisoinosine and Related 2′-Deoxyribonucleosides

✍ Scribed by Frank Seela; Yaoming Chen; Uwe Bindig; Zygmunt Kazimierczuk


Publisher
John Wiley and Sons
Year
1994
Tongue
German
Weight
563 KB
Volume
77
Category
Article
ISSN
0018-019X

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Stereocontrolled synthesis of α-2′-deoxy
✍ Zhiwei Wang; Carmelo J Rizzo 📂 Article 📅 1997 🏛 Elsevier Science 🌐 French ⚖ 225 KB

A stereocontrolled synthesis of c¢-2'-deoxynucleosides has been achieved. Our synthetic strategy involves the use of a benzoyl group at the 2-position of arabinose as a directing group for Vorbrtiggen glycosylation and a deoxygenation precursor.

Synthesis of 6-Substituted 1-Deazapurine
✍ Thomas Wenzel; Frank Seela 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 German ⚖ 590 KB

## Abstract The synthesis of 6‐substituted 1‐deazapurine 2′‐deoxyribonucleosides is described. Glycosylation of the 1‐deazapurine (imidazo[4,5‐__b__]pyridine) anions with the α‐D‐halogenose 5 gives stereoselectively __N__^7^‐ and __N__^9^‐ regioisomers. ^1^H‐NMR NOE and ^13^C‐NMR spectroscopy are u

7-Halogenated 7-Deazapurine 2′-Deoxyribo
✍ Frank Seela; Kuiying Xu 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 German ⚖ 409 KB

## Abstract A series of 7‐fluorinated 7‐deazapurine 2′‐deoxyribonucleosides related to 2′‐deoxyadenosine, 2′‐deoxyxanthosine, and 2′‐deoxyisoguanosine as well as intermediates **4b**–**7b, 8, 9b, 10b**, and **17b** were synthesized. The 7‐fluoro substituent was introduced in 2,6‐dichloro‐7‐deaza‐9_

Synthesis of 9-Halogenated 9-Deazaguanin
✍ Frank Seela; Khalil I. Shaikh; Thomas Wiglenda; Peter Leonard 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 German ⚖ 203 KB

## Abstract The syntheses of __N__^7^‐glycosylated 9‐deazaguanine **1a** as well as of its 9‐bromo and 9‐iodo derivatives **1b**,**c** are described. The regioselective 9‐halogenation with __N__‐bromosuccinimide (NBS) and __N__‐iodosuccinimide (NIS) was accomplished at the protected nucleobase **4a