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Synthesis of 2-(Bicyclo[2.2.1]hept-2-yloxy)ethyl Carboxylates

โœ Scribed by A. G. Gasanov; A. V. Nagiev


Book ID
106523654
Publisher
SP MAIK Nauka/Interperiodica
Year
2005
Tongue
English
Weight
88 KB
Volume
41
Category
Article
ISSN
1070-4280

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Synthesis of ethyl 1-azabicyclo[2.2.1]he
โœ Barry S. Orlek; Harry Wadsworth; Paul Wyman; Frank D. King ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 117 KB

The dipolar cycloaddition reaction of a-methylene butyrolactone and N-benzyl azomethine ylid (5) affords the spirolactone (2) which rearranges to give ethyl 1-azabicyclo[2.2.l]hept-Cyl carboxylate (1) in excellent overall yield.