Synthesis of ethyl 1-azabicyclo[2.2.1]he
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Barry S. Orlek; Harry Wadsworth; Paul Wyman; Frank D. King
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Article
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1991
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Elsevier Science
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French
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The dipolar cycloaddition reaction of a-methylene butyrolactone and N-benzyl azomethine ylid (5) affords the spirolactone (2) which rearranges to give ethyl 1-azabicyclo[2.2.l]hept-Cyl carboxylate (1) in excellent overall yield.