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Synthesis of 2-aryltryptamines with palladium catalyzed cross-coupling of 2-bromotryptamines and arylboronic acids

โœ Scribed by Lin Chu; Michael H. Fisher; Mark T. Goulet; Matthew J. Wyvratt


Book ID
104257158
Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
201 KB
Volume
38
Category
Article
ISSN
0040-4039

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โœฆ Synopsis


A versatile and high-yielding synthesis of 2-aryltryptamines employing palladium(O) catalyzed cross-coupling of 2-bromotryptamines and arylboronic acids was developed. The preparation of the intermediate 2-bromotryptamines with pyridine hydrobromide perbromide as the brominating agent, is also reported.


๐Ÿ“œ SIMILAR VOLUMES


Palladium-catalyzed cross-coupling react
โœ S. Tumkevicius; J. Dodonova; I. Baskirova; A. Voitechovicius ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› Journal of Heterocyclic Chemistry ๐ŸŒ English โš– 85 KB

## Abstract magnified image The Suzukiโ€Miyaura reaction of some 4,6โ€dichloropyrimidines bearing methylthioโ€, methylโ€, aminoโ€, cyanoโ€, formylโ€, and nitro groups in positions 2 and/or 5 of the pyrimidine ring with arylboronic acids has been investigated. Influence of palladium catalyst, ligand, base