Synthesis of 2-aryl-imidazo[4,5-d][1,2,3]triazoles from a 4-nitro-imidazol-5-yl phosphoramidate and aryl isocyanates
โ Scribed by Abutariq Taher; Sandra Eichenseher; George W Weaver
- Book ID
- 104211305
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- French
- Weight
- 46 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0040-4039
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โฆ Synopsis
The synthesis of a series of 2-aryl-2H, 4H-imidazo[4,5-d][1,2,3]triazoles is reported. These compounds are obtained in moderate to good yield by reaction of triethyl N-1-ethyl-2-methyl-4-nitro-1H-imidazol-5yl phosphoramidate with aryl isocyanates.
๐ SIMILAR VOLUMES
Condensation of 4-methylsulfonylaniline with aryl aldehyde in ethanol-tetrahydrofuran afforded the imino compound 3. 1,3-Cycloaddtion of diazomethane with compound 3 followed by oxidazation of the triazoline 4 with potassium permanganate gave 1-(4-methylsulfonylphenyl)-5-aryl-1,2,3-triazoles 5. Simi