Synthesis of 2-aminoindoles from N-acylamino derivatives of tetrahydroquinoline
โ Scribed by N. V. Shorina; G. A. Golubeva; L. A. Sviridova; V. N. Torocheshnikov
- Publisher
- Springer US
- Year
- 1990
- Tongue
- English
- Weight
- 176 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0009-3122
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๐ SIMILAR VOLUMES
In the course of our investigation towards the design and synthesis of potential immunomodulators related to muramyldipeptide'), N-acylaminoethoxyacetic acid derivatives were needed as valuable key intermediates for the synthesis of some model compounds. Such aliphatic amino acid compounds in which
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BF3.Et20 or Yb(OTf)3 catalyzed [4+2] cycloaddition reaction of ct-CF3-N-arylaldimines with nucleophilic olefins afforded CF3-substituted tetrahydroquinoline derivatives.