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Synthesis of 2-amino-9-(3′-azido-2′,3′-dideoxy-beta-D-erythro-pentofuranosyl)-6-methoxy-9H purine (AzddMAP) and AzddGuo

✍ Scribed by M.R. Almond; J.L. Collins; B.E. Reitter; J.L. Rideout; G.A. Freeman; M.H. St. Clair


Book ID
118392490
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
46 KB
Volume
15
Category
Article
ISSN
0166-3542

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📜 SIMILAR VOLUMES


Synthesis of 2-amino-9-(3′-azido-2′,3′-d
✍ Merrick R. Almond; Jon L. Collins; Barbara E. Reitter; Janet L. Rideout; G.Andre 📂 Article 📅 1991 🏛 Elsevier Science 🌐 French ⚖ 271 KB

A novel synthesis of AzddMAP and AzddGuo is described starting from 1, ## 2-0-isopropylidene-alpha-D-xylofuranose. The key step in this synthesis involves the replacement of a diphenyl carbamoyl protecting group in the purine 6-position by methanol. In 1987 Hartmann, Hunsmann, and Eckstein (1) re

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