Synthesis of 2-alkyl-3-aryl-substituted quinuclidines as novel dopamine transporter inhibitors

✍ Scribed by Sukumar Sakamuri‡; Istvan J Enyedy†; §; ∣∣; Alan P Kozikowski†; ‡; Shaomeng Wang†; §; ∣∣

• Book ID: 104211355
• Publisher: Elsevier Science
• Year: 2000
• Tongue: French
• Weight: 148 KB
• Volume: 41
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)01810-4

✦ Synopsis

The synthesis of 2-alkyl-3-aryl-substituted quinuclidines was accomplished in a simple synthetic sequence. The separation of enantiomers was carried out using chiral HPLC.