Synthesis of 2, 6-derivatives of 1, 4-dioxane
โ Scribed by S. B. Zotov; V. V. Smirnov; F. V. Kvasnyuk-Mudryi; V. I. Shevchenko
- Book ID
- 112328700
- Publisher
- Springer US
- Year
- 1970
- Tongue
- English
- Weight
- 127 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0009-3122
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Methyl 4-(5-nitro-1,3-dioxaspiro[5.5] undecan-5-yl)but-2-enoate 2, obtained from the palladium(0)-catalyzed reaction of a salt of 5-nitro-1,3-dioxane 1 with methyl g-bromocrotonate, was converted into the title piperidinone (ee 78%) in three steps.
Synthesis of 5-[(Indol-2-on-3-yl)methyl]-2,2-dimethyl-1,3-dioxane-4,6diones and Spirocyclopropyloxindole Derivatives. Potential Aldose Reductase Inhibitors. -Indoles (I) are transformed into indolyl derivatives (IV) following a literature process. Subsequent reaction with 1 equiv. of NBS generates