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Synthesis of 2-(3-spiro-cyclohexyl-3,4-dihydroisoquinolyl-1)acetic acid derivatives and their effects on blood clotting

✍ Scribed by A. G. Mikhailovskii; N. N. Polygalova; N. G. Ismailova; B. Ya. Syropyatov; M. I. Vakhrin

Book ID: 106491828
Publisher: Springer
Year: 2008
Tongue: English
Weight: 95 KB
Volume: 42
Category: Article
ISSN: 0091-150X
DOI: 10.1007/s11094-008-0082-1

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## Abstract A series of the title spirocyclic benzopyran derivatives (XI) (12 examples) is synthesized, which all prove to be selective inhibitors of aldose reductase (ARL2).