𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of 1α,25-dihydroxyvitamin D2, its 24 epimer and related isomers, and their binding affinity for the 1,25-dihydroxyvitamin D3 receptor

✍ Scribed by Rafal R. Sicinski; Yoko Tanaka; Heinrich K. Schnoes; Hector F. DeLuca

Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
815 KB
Volume
13
Category
Article
ISSN
0045-2068

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Binding characteristics of a membrane re
Binding characteristics of a membrane receptor that recognizes 1α25-dihydroxyvitamin D3 and its epimer, 1β,25-dihydroxyvitamin D3
✍ Daniel T. Baran; Rahul Ray; Ann Marie Sorensen; Thomas Honeyman; Michael F. Holi 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 576 KB

The steroid hormone Ia,25-dihydroxyvitamin D3 has been shown to exert rapid effects (1 5 s to 5 min) in osteoblasts. These effects occur in osteoblast-like cells lacking the nuclear vitamin D receptor, ROS 24/1, suggesting that a separate signalling system mediates the rapid actions. These non-genom

1α,25-Dihydroxyvitamin D3-3β-(2)-bromoac
1α,25-Dihydroxyvitamin D3-3β-(2)-bromoacetate, an affinity labeling derivative of 1α,25-dihydroxyvitamin D3 displays strong antiproliferative and cytotoxic behavior in prostate cancer cells
✍ Narasimha Swamy; Kelly S. Persons; Tai C. Chen; Rahul Ray 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 219 KB

In this report we describe that 1,25(OH)(2)D(3)-3-BE, a VDR-affinity labeling analog of 1,25(OH)(2)D(3), showed strong and dose-dependent growth-inhibitory effect in several epithelial cells, i.e., keratinocytes (primary cells), MCF-7 breast cancer, PC-3, and LNCaP prostate cancer and PZ-HPV-7 immor