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Synthesis of [17α, 16α] oxazolino steroids specifically labelled in C-2′ of the oxazoline ring with 14C

✍ Scribed by Giuseppe Sartori; Giorgio Winters

Publisher
John Wiley and Sons
Year
1980
Tongue
French
Weight
276 KB
Volume
17
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

The preparation of ^14^C‐labelled 11β, 21‐dihydroxy‐3,20‐dioxy‐pregna‐1,4‐dieno[ 17α, 16α‐d]‐2′‐methyloxazoline‐21‐acetate and of 9α‐fluoro‐11β,21‐dihydroxy‐3,20‐dioxopregna‐l,4‐dieno[ 17α,16α ]‐2′‐methyloxazoline‐21‐acetatelNote that [17α., 160α‐d] does not refer to deuterium labelling

is described. Specific labelling at the C‐2′ position was achieved reacting the corresponding 17α‐amino‐16α‐alcohols with [1‐^14^C]‐acetic anhydride.

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The synthesis of α-methylstyrenes with 1
The synthesis of α-methylstyrenes with 14C-labelling in the side chain
✍ H. M. Ali; C. A. Barson; P. L. Coe 📂 Article 📅 1984 🏛 John Wiley and Sons 🌐 French ⚖ 154 KB

## Abstract α‐Methylstyrenes with all three side chain carbons specifically ^14^C‐labelled have been synthesised by Wittig reactions between the appropriately labelled acetophenones or methylene triphenylphosphoranes. The yields in all cases were good and any radiochemical impurities could be readi