5-Nitro-2,4-dihydro-3H-l,2,4-triazol-3-one (NTO) has been synthesized in good yield with 15N at the 1 and 2 positions. The N-H coupling provides unequivocal assignments for I H and 15N NMR spectra and the acidic proton. The products of thermal decomposition at 270 O C were identified spectroscopical
✦ LIBER ✦
Synthesis of 15N-Labelled D-Isovaline and α-Aminoisobutyric Acid
✍ Scribed by Andrei Ogrel; Vitalii I. Shvets; Bernard Kaptein; Quirinus B. Broxterman; Jan Raap
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 201 KB
- Volume
- 2000
- Category
- Article
- ISSN
- 1434-193X
No coin nor oath required. For personal study only.
✦ Synopsis
15
N]-D-isovaline was prepared from DL-[α-15 N]-α-aminoisovaleramide by enzymatic resolution with Mycobacterium neoaurum. The 15 N-isotope was introduced during the Strecker synthesis
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