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Synthesis of 14C-labelled 2-(p-chloro-α-hydroxybenzyl)-benzimidazole (HBBPC)

✍ Scribed by A. Durand; C. Beney; C. Luu Duc; Cl. Agnius Delord


Publisher
John Wiley and Sons
Year
1981
Tongue
French
Weight
118 KB
Volume
18
Category
Article
ISSN
0022-2135

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✦ Synopsis


Abstract

p‐Chloro[^14^C]mandelic acid 2 was prepared from [^14^C]potassium cyanide and p‐chlorobenzaldehyde 1. The condensation of p‐chloro[^14^c] mandelic acid with 1,2‐diamino benzene 3 gave the title benzimidazole 4 labelled at the carbon atome 2 of the heterocyclic ring.


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