## Abstract On alkylation of K^14^CN with the methyl ester of L‐α‐benzyl‐oxycarbonylamino‐γ‐bromobutyric acid, the methyl ester of L‐α‐benzyloxycarbonylamino‐γ‐cyano‐^14^C‐butyric acid (II) was obtained The latter was submitted to mild alkaline hydrolysis to yield the free nitrilo acid III which on
Synthesis of [14C]-L-α-aspartyl-L-pheylalanine ([14C]-aspartame acid)
✍ Scribed by Richard C. Durley
- Publisher
- Elsevier Science
- Year
- 1988
- Weight
- 66 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0883-2889
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Syntheses are described from a common labeled intermediate of P-cyanoalanine, asparagine, and aspartic acid, each of the L conjiguration and labeled with carbon-14 in carbon-four. Radiochemical purities were 96, 99.7, and 99 %. The common source of carbon-14 was ethyl aCetyl-DL-P-~yanoalaninate-4-~~
The synthesis o f three carbon-I4
## Abstract Two labeled isotopomers of L‐tyrosine, L‐Tyr, have been synthesized using specific properties of the enzymes phenylanine ammonia lyase, PAL, and L‐phenylalanine hydroxylase. In an intermediate step [1‐^14^C]‐, and [2‐^14^C]‐L‐phenylalanine, L‐Phe, have been obtained from [1‐^14^C]‐, and