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Synthesis of 14C-acanthoic acid

✍ Scribed by Sung-Whi Rhee; Jeremiah P. Malerich; Jung-Joon Lee; Mary J. Tanga


Book ID
112132913
Publisher
John Wiley and Sons
Year
2012
Tongue
French
Weight
109 KB
Volume
55
Category
Article
ISSN
0022-2135

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## Abstract L‐ascorbic‐6‐^14^C acid with a specific activity of 3.25 ΞΌCi/mg was prepared from D‐glucose‐1‐^14^C in an overall yield of 10 %. Synthetic steps were : glucose to sorbitol, sorbose, diisopropylidene sorbose, potassium diisopropylidene 2‐ketogulonate, 2‐ketogulonic acid and ascorbic acid