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Synthesis of 1,4-Diphenylbutadiene Derivatives: Novel Inducer of Tissue-Type Plasminogen Activator (t-PA) in Cultured Bovine Endothelial Cells.

✍ Scribed by Hiroshi Sai; Tsuyoshi Ogiku; Hiroshi Ohmizu; Akio Ohtani


Publisher
John Wiley and Sons
Year
2007
Weight
39 KB
Volume
38
Category
Article
ISSN
0931-7597

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The effects were examined of baicalein on tissue-type plasminogen activator (t-PA) and plasminogen activator inhibitor-1 (PAI-1) production stimulated by interleukin-1␣ (IL-1␤) and tumour necrosis factor-␣ (TNF-␣) in cultured human vein umbilical endothelial cells (HUVECs). IL-1␤ and TNF-␣ increased