✦ LIBER ✦

Synthesis of 13C-labeled chenodeoxycholic, hyodeoxycholic, and ursodeoxycholic acids for the study of bile acid metabolism in liver disease

✍ Scribed by S. Matern; H.-U. Marschall; A. Schill; B. Schumacher; W. Lehnert; J. Sjövall; H. Matern

Book ID: 115827164
Publisher: Elsevier Science
Year: 1991
Tongue: English
Weight: 856 KB
Volume: 203
Category: Article
ISSN: 0009-8981
DOI: 10.1016/0009-8981(91)90158-9

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Metabolism of stable isotope labeled bil

Metabolism of stable isotope labeled bile acids in extrahepatic cholestasis and liver cirrhosis of man: 6α-hydroxylation of (24-13C)chenodeoxycholic and of (24-13C) ursodeoxycholic acids

✍ H.-U. Marschall; H. Matern; H. Schill; B. Schumacher; W. Lehnert; S. Matern 📂 Article 📅 1988 🏛 Elsevier Science ⚖ 79 KB

A two-year prospective study of the effe

A two-year prospective study of the effect of ursodeoxycholic acid on urinary bile acid excretion and liver morphology in cystic fibrosis–associated liver disease

✍ Anders Lindblad; Hans Glaumann; Birgitta Strandvik 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 284 KB 👁 1 views

The efficacy of 2 years of treatment with ursodeoxycholic acid (UDCA) in cystic fibrosis (CF)-associated liver disease was evaluated by liver biopsies and liver function tests in 10 patients aged 8 to 28 years. The metabolism of UDCA was investigated by analysis of urinary bile acids with fast atom

Effect of ursodeoxycholic acid on the ki

Effect of ursodeoxycholic acid on the kinetics of the major hydrophobic bile acids in health and in chronic cholestatic liver disease

✍ Ulrich Beuers; Ulrich Spengler; Franz M. Zwiebel; Juergen Pauletzki; Sven Fische 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 619 KB

Beneficial effects of ursodeoxycholic acid in chronic cholestatic liver diseases have been attributed to displacement of hydrophobic bile acids from the endogenous bile acid pool. To test this hypothesis, we determined pool sizes, fractional turnover rates, synthesis/input rates and serum levels of

Metabolism of chyle triglycerides in the

Metabolism of chyle triglycerides in the liver: I. Studies on the mechanisms for liver uptake of intravenously injected, glycerol- and fatty acid-labeled chyle in the carbohydrate-fed rat

✍ P. Belfrage 📂 Article 📅 1966 🏛 Elsevier Science 🌐 English ⚖ 926 KB

An in Situ NMR Study of the Mechanism fo

An in Situ NMR Study of the Mechanism for the Catalytic Conversion of Fructose to 5-Hydroxymethylfurfural and then to Levulinic Acid Using 13 C Labeled d -Fructose

✍ Zhang, Jing; Weitz, Eric 📂 Article 📅 2012 🏛 American Chemical Society 🌐 English ⚖ 621 KB

Isotopically labelled tropane alkaloids.

Isotopically labelled tropane alkaloids. The synthesis of (RS)-[3′, 3′-2H2]- and (RS)-[1′-13C, 3′, 3′-2H2]- hyoscyamines for metabolism studies in plants

✍ Stephen Patterson; David O'Hagan 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 French ⚖ 101 KB 👁 1 views

## Abstract A synthetic route to isotopically labelled forms of the tropane alkaloid hyoscyamine, including (__RS__)‐[3′, 3′,‐^2^H~2~]‐ (**2a**) and (__RS__)‐[1′‐^13^C, 3′, 3′,‐^2^H~2~]‐ (**2b**) hyoscyamines, involving the reaction between phenylacetyl tropine and formaldehyde is described. The is