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Synthesis of 1,3,5-triazabicyclo[3.1.0]hexanes containing the fragments of α-amino acids and their esters at the N(3) atom

✍ Scribed by A.V. Shevtsov; V.Yu. Petukhova; N.N. Makhova


Book ID
111607500
Publisher
Springer
Year
2003
Tongue
English
Weight
283 KB
Volume
52
Category
Article
ISSN
1573-9171

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1-Chlorocyclopropyl p-tolyl sulfoxides bearing an alkoxymethyl group at the 2-position were easily prepared from a,b-unsaturated esters with dichloromethyl p-tolyl sulfoxide and alkylhalides in three steps in good overall yields. Treatment of the 1-chlorocyclopropyl p-tolyl sulfoxides with i-PrMgCl