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Synthesis of 1,3-Amino Alcohol Derivatives via a Silicon-Mediated Ring-Opening of Substituted Piperidines

✍ Scribed by McCall, W. Stephen; Comins, Daniel L.


Book ID
126820024
Publisher
American Chemical Society
Year
2009
Tongue
English
Weight
162 KB
Volume
11
Category
Article
ISSN
1523-7060

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Synthesis of alicyclic N-substituted 1,3
✍ Árpád Balázs; Zsolt Szakonyi; Ferenc Fülöp 📂 Article 📅 2007 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 286 KB

## Abstract magnified image Alicyclic __N__‐substituted 1,3‐amino alcohols **13‐18** were prepared in a facile way in a one‐pot procedure from 1,3‐oxazines **5‐8** in the presence of a ketone **9‐12**. The complex reaction involves palladium‐catalyzed reduction, debenzylation and/or transimination