Synthesis of 1,2,3,4,5,6,7,10-Octahydro-1,5-imino-7,10-dioxo-3-benzazocine-4-carbonit rile Derivative and Evaluation of Antitumor Activity Related to Saframycin and Renieramycin Isoquinolinequinones.
β Scribed by Yu-ichi Koizumi; Ken-ichi Inamura; Akinori Kubo; Naoki Saito
- Publisher
- John Wiley and Sons
- Year
- 2007
- Weight
- 13 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0931-7597
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Synthesis of Novel Octahydro-1,5-imino-3-benzazocin-4,7,10-trione Derivatives Having a Methyl Group at the C-2 Position as ABC Ring Models of Saframycins. -Simple and efficient syntheses of (Z)-3-benzylidenepiperazinedione ( VII) in both racemic and optically active forms are described. Compound (V