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Synthesis of [11C]PBR170, a novel imidazopyridine, for imaging the translocator protein with PET

✍ Scribed by Bourdier, Thomas; Henderson, David; Fookes, Christopher J.R.; Lam, Peter; Mattner, Filomena; Fulham, Michael; Katsifis, Andrew


Book ID
122276584
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
685 KB
Volume
90
Category
Article
ISSN
0969-8043

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Radiosynthesis of [18F]PBR111, a selecti
✍ Frédéric Dollé; Françoise Hinnen; Annelaure Damont; Bertrand Kuhnast; Christophe 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 French ⚖ 137 KB

## Abstract PBR111 (2‐(6‐chloro‐2‐(4‐(3‐fluoropropoxy)phenyl)imidazo[1,2‐__a__]pyridin‐3‐yl)‐__N__,__N__‐diethylacetamide) is a novel, reported, high‐affinity and selective ligand for the translocator protein (18 kDa). PBR111 has been labelled with fluorine‐18 (half‐life: 109.8 min) using our Zymat