𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A practical process for the synthesis of translocator protein 18kDa imidazopyridine ligand

✍ Scribed by Wen, Meng; Qu, Chunrong; Su, Xinhui; Ding, Mingmin; Deng, Zixin; Hong, Xuechuan


Book ID
121578668
Publisher
Wuhan University
Year
2014
Tongue
English
Weight
509 KB
Volume
19
Category
Article
ISSN
1007-1202

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Radiosynthesis of [18F]DPA-714, a select
✍ Annelaure Damont; Françoise Hinnen; Bertrand Kuhnast; Marie-Anne Schöllhorn-Peyr 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 French ⚖ 193 KB

## Abstract Recently, a novel series of 2‐phenylpyrazolo[1,5‐__a__]pyrimidineacetamides has been reported as selective ligands of the translocator protein (18 kDa). Within this series, DPA‐714 (__N,N__‐diethyl‐2‐(2‐(4‐(2‐fluoroethoxy)phenyl)‐5,7‐dimethylpyrazolo[1,5‐__a__]pyrimidin‐3‐yl)acetamide,

Radiosynthesis of [18F]PBR111, a selecti
✍ Frédéric Dollé; Françoise Hinnen; Annelaure Damont; Bertrand Kuhnast; Christophe 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 French ⚖ 137 KB

## Abstract PBR111 (2‐(6‐chloro‐2‐(4‐(3‐fluoropropoxy)phenyl)imidazo[1,2‐__a__]pyridin‐3‐yl)‐__N__,__N__‐diethylacetamide) is a novel, reported, high‐affinity and selective ligand for the translocator protein (18 kDa). PBR111 has been labelled with fluorine‐18 (half‐life: 109.8 min) using our Zymat

The development of PET radioligands for
✍ Christopher Luus; Raphy Hanani; Aaron Reynolds; Michael Kassiou 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 French ⚖ 208 KB

## Abstract The translocator protein (TSPO; 18 kDa), formerly known as the peripheral benzodiazepine receptor (PBR), is minimally expressed in the healthy brain. On the other hand, increased levels of TSPO have been noted in brain disorders for which an immune response is elicited. This increase in