Synthesis of 11-aminodibenzo[b,f][1,4]thiazepines and fluoro derivatives
✍ Scribed by Yvette Mettey; Jacques Lehuede; Jean-Michel Vierfond
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1997
- Tongue
- English
- Weight
- 193 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0022-152X
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
The reaction of balogenobenzonitriles with 2‐aminobenzenethiol is a new route, in a “one‐pot” or two‐step approach, to 11‐aminodibenzo[b,f][1,4]thiazepine and fluoro derivatives.
📜 SIMILAR VOLUMES
## Abstract magnified image A convenient synthesis of the novel dibenzo[__b,f__][1,4]thiazepin‐11(10__H__)‐ones is reported. As a key step, the synthetic route includes intramolecular aromatic denitrocyclization of 2‐(2,4‐dinitro‐phenylsulfanyl)‐benzoic acid amides. Efficient procedures for denitr
## Abstract Treatment of 5‐methylthio‐2,3‐dihydrothieno[3,2‐__f__]‐1,4‐thiazepine (9) with acylhydrazines gave 5,6‐dihydrothieno[3,2‐__f__]‐1,2,4‐triazolo[4,3‐__d__][1,4]thiazepines 10, 11, and that of 9 with ethyl anthranilate gave 5,6‐dihydrothieno[3′,2′:6,7][1,4]thiazepino[5,4‐__b__]quinazolin‐8
## Abstract The S‐amination of 9__H__‐thioxanthen‐9‐ol (**2a**) and 9‐substituted derivatives **2b**–**e** (Me (**b**), Et (**c**), ^i^Pr (**d**), Ph (**e**)) with O‐mesitylenesulfonylhydroxylamine (MSH) was carried out. The expected product, 10‐amino‐9‐hydroxy‐9‐isopropyl‐9__H__‐thioxanthenium mes