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New method for the preparation of dibenzo[b, f][1,4]thiazepines

✍ Scribed by Takayoshi Fujii; Wei Hao; Toshiaki Yoshimura

Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
104 KB
Volume
15
Category
Article
ISSN
1042-7163

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✦ Synopsis

Abstract

The S‐amination of 9__H__‐thioxanthen‐9‐ol (2a) and 9‐substituted derivatives 2b–e (Me (b), Et (c), ^i^Pr (d), Ph (e)) with O‐mesitylenesulfonylhydroxylamine (MSH) was carried out. The expected product, 10‐amino‐9‐hydroxy‐9‐isopropyl‐9__H__‐thioxanthenium mesitylenesulfonate (3d), was obtained in 78(%) yield from the corresponding thioxanthen(9)‐ol 2d. However, in the case of 2a–c and 2e the reaction led instead to dibenzo[b,f][1,4]thiazepines 6a–c and 6e in moderate yields. © 2004 Wiley Periodicals, Inc. Heteroatom Chem 15:246–250, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20010

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