Synthesis of 10,11-Didehydro Cinchona Alkaloids and Key Derivatives
✍ Scribed by Wilfried M. Braje; Jens Frackenpohl; Olaf Schrake; Rudolf Wartchow; W. Beil; H. Martin R. Hoffmann
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- German
- Weight
- 206 KB
- Volume
- 83
- Category
- Article
- ISSN
- 0018-019X
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## Abstract A revised procedure for the conversion of the four major __Cinchona__ alkaloids (quinine, quinidine, cinchonidine, and cinchonine) into their respective 10,11‐didehydro derivatives is described. The reported protocol offers several advantages over a recently published synthetic route. T
Part One -- Cinchona Alkaloid Derivatives As Chirality Inducers In Metal-catalyzed Reactions -- Part Two -- Cinchona Alkaloid Derivatives As Chiral Organocatalysts -- Part Three -- Organic Chemistry Of Cinchona Alkaloids -- Part Four -- Cinchona Alkaloid And Their Derivatives In Analytics. Edited By
Part One -- Cinchona Alkaloid Derivatives As Chirality Inducers In Metal-catalyzed Reactions -- Part Two -- Cinchona Alkaloid Derivatives As Chiral Organocatalysts -- Part Three -- Organic Chemistry Of Cinchona Alkaloids -- Part Four -- Cinchona Alkaloid And Their Derivatives In Analytics. Edited By
## Abstract The X‐ray crystal analyses of the two 11‐deoxy‐didehydrohexahydrobenzo[__c__]phenanthridine‐type alkaloid derivatives **3** and **4**, derived from (±)‐corynoline (**1**) and (+)‐chelidonine (**2**), established their structures as (±)‐(5b__RS__,12b__RS__)‐5b,12b,13,14‐tetrahydro‐5b,13‐