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Synthesis of 1-(α-phenylethyl)azetidin-2-ones

✍ Scribed by N. N. Romanova; V. A. Budylin; G. V. Grishina; V. M. Potapov; V. N. Torocheshnikov; M. L. Demchuk; Yu. G. Budel'


Book ID
112348736
Publisher
Springer US
Year
1984
Tongue
English
Weight
325 KB
Volume
20
Category
Article
ISSN
0009-3122

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Synthesis of optically active azetidin-2
✍ Hiroaki Yanagisawa; Akiko Ando; Masao Shiozaki; Tetsuo Hiraoka 📂 Article 📅 1983 🏛 Elsevier Science 🌐 French ⚖ 224 KB

In a previous paper1 we described the stereocontrolled synthesis of the 3S-(lR-hyroxyethyl)-4R-carboxyazetidin-Z-one derivative, an important intermediate of the from the carbapenem antibiotics, from L-threonine. Our strategy was as follows: the negatively charged 2 carbon in 2 prepared from L-thre