Stereoselective Synthesis of 1,3-Disubstituted Hexahydro-1,4diazepin-2-ones. -A fast and facile asymmetric synthesis of the title compounds (VI), a kind of constrained peptides, involving the diastereoselective alkylation of optically pure hydroxylactam (IV) as the key step is described.
โฆ LIBER โฆ
Facile Stereoselective Synthesis of 1,3-Disubstituted-4-trichloromethyl Azetidin-2-ones.
โ Scribed by V. V. Govande; A. R. A. S. Deshmukh
- Publisher
- John Wiley and Sons
- Year
- 2004
- Weight
- 22 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0931-7597
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