Synthesis of 1-(substituted-aryl) methylthiomethanephosphonates by Friedel-Crafts reaction of aromatic compounds with chloro(methylthio)methanephosphonate
✍ Scribed by Taek Hyeon Kim; Dong Young Oh
- Book ID
- 104218289
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- French
- Weight
- 112 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0040-4039
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An efficient Friedel-Crafts alkylation of aromatic compounds with ethyl a-chloro-a-(ethylthio)acetate catalysed by ytterbium triflate, followed by desulfurisation of the product provides a convenient methodology for the synthesis of ethyl arylacetates of aromatic and heteroaromatic compounds.
## Abstract The reaction of 1,3‐bis(trimethylsilyloxy)‐1,3‐butadienes with 3‐benzoyl‐5‐aryl‐4,5‐dihydrofurans, available by CAN‐mediated reaction of styrenes with benzoylacetones, afforded functionalized 9,10‐dihydrophenanthrenes. These reactions proceed by a novel domino [3+3] cyclization/ring‐ope