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Synthesis of 1-arylsulfonyl-4-arylpiperazines with a sterically hindered nitrogen atom

✍ Scribed by S. I. Burmistrov; N. V. Makarevich; L. Ya. Kravchenko


Book ID
112328020
Publisher
Springer US
Year
1976
Tongue
English
Weight
270 KB
Volume
12
Category
Article
ISSN
0009-3122

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Synthesis of sterically hindered 4a, 9a-
✍ JoseΒ΄Gonzalo RodriΒ΄guez; AnahiΒ΄ Urrutia πŸ“‚ Article πŸ“… 1998 πŸ› Elsevier Science 🌐 French βš– 382 KB

The reaction of 4a-methyl-l,2,3,4-tetrahydrocarbazole (1) with organolithium reagents affords the sterically hindered alkyl, aryl or alkenyl cis-4a-methyl-9a-substituted-l,2,3,4,4a,9ahexahydrocarbazole derivatives (2) in excellent yields. Two diastereomeric pairs were isolated for the 9a-see-butyl d