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Synthesis of 1-(3-trideuteromethoxy-4-hydroxyphenyl)-[1,2,2-2H3]-ethyleneglycol ([2H6]MHPG)

โœ Scribed by S Murray; T A Baillie; D S Davies


Publisher
John Wiley and Sons
Year
1981
Tongue
French
Weight
197 KB
Volume
18
Category
Article
ISSN
0022-2135

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โœฆ Synopsis


Abstract

The four stage synthesis of a hexadeuterated analogue of the noradrenaline metabolite 3โ€methoxyโ€4โ€hydroxyphenylethylene glycol (MHPG) is described. The overall yield from 3โ€trideuteromethoxyโ€4โ€hydroxyacetophenone is 29%.


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