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Synthesis of [1-14C]butyl, [13C2-dimethyl]butyl and [2H6-dimethyl]butyl-neotame

✍ Scribed by Thomas Winwick; Roger D. Barnes

Publisher
John Wiley and Sons
Year
2007
Tongue
French
Weight
69 KB
Volume
50
Category
Article
ISSN
0022-2135

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Synthesis of sodium 6-isopropyl-3-[4-(P-
Synthesis of sodium 6-isopropyl-3-[4-(P-chlorobenzenesulfonylamino)-butyl]-[2-14C]azulene-1-sulfonate
✍ Takashi Yanagisawa; Masayuki Yokota; Tsuyoshi Tomiyama; Shiro Ikegami 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 French ⚖ 330 KB

## Abstract Sodium 6‐isopropyl‐3‐[4‐(p‐chlorobenzenesulfonylamino)‐butyl]azulene‐l‐sulfonate (KT2‐962) 1, which has been found to be a potent and selective thromboxaneA~2~ receptor antagonist, was synthesized in ^14^C‐labelled form by using potassium [^14^C]‐cyanide. ^14^C‐labelled 1 with a specif