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Synthesis of [1-13C] and stereo-specifically [1-2H] labeled fluorinated substrate analogues of IspH enzyme in the deoxyxylulose phosphate pathway

โœ Scribed by Youli Xiao; Pinghua Liu


Book ID
108285292
Publisher
Elsevier Science
Year
2009
Tongue
French
Weight
295 KB
Volume
50
Category
Article
ISSN
0040-4039

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Isotopically labelled tropane alkaloids.
โœ Stephen Patterson; David O'Hagan ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 101 KB ๐Ÿ‘ 1 views

## Abstract A synthetic route to isotopically labelled forms of the tropane alkaloid hyoscyamine, including (__RS__)โ€[3โ€ฒ, 3โ€ฒ,โ€^2^H~2~]โ€ (**2a**) and (__RS__)โ€[1โ€ฒโ€^13^C, 3โ€ฒ, 3โ€ฒ,โ€^2^H~2~]โ€ (**2b**) hyoscyamines, involving the reaction between phenylacetyl tropine and formaldehyde is described. The is